According to the information provided, supplements with high CFU (colony-forming units) of healthy bacteria typically start to produce noticeable benefits for digestive health in 4-8 weeks. Since Floraspring has a lower CFU count, it is suggested that it may take at least 3-4 months to notice these benefits. However, it is also mentioned that Floraspring is not primarily a weight loss supplement, and its effectiveness in this regard is questionable.